I don't know about 2, but for 1 you could include another contact method in the autoresponse that the user needs to go thru to get your email. Either give your phone number, if they are close contacts, or send them to a contact details web page where they can get your new address from. (and give them the option to download a vCard of your details so the extra step doesn't seem as much of a pain)
I'd be surprised if a spammer had a system that would read an incoming email, extract web pages links from it, then extract emails from that page - but it would be possible.
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